SCIENCE
REFERENCES
SCIENCE
REFERENCES
January 2010
Authors:
The importance of stem cells and stem cell regenerative medicine in healing, regenerating, rejuvenating the body; decreasing morbidity and mortality; and making the impossible possible cannot be overlooked. Obtaining stem cells was historically restricted to the harvesting of embryonic, cord blood, and adult stem cells, which made stem cell therapy an expensive, invasive, and a complicated process. However, the technology for generating nano silver, which has the ability to activate stem cells, has progressed by leaps and bounds during the last 20 years. This paper highlights the use of nano silver in the activation of in vivo stem cells. This has enabled stem cell therapy to be i) safe, ii) easy to derive, iii) user-friendly, iv) inexpensive, v) with no adverse effects, and vi) with no morbidity normally involved in the harvesting of stem cells. Today, in vivo stem cell activation using nano silver has vastly reduced the need for costly and complicated methods of harvesting and using embryonic, cord blood, and adult stem cells. As a result, this has brought the common man closer to the benefits of stem cell regenerative medicine at a very reasonable and affordable cost. Once the exclusive domain of high cost medical treatment, in vivo stem cell activation has made available stem cell therapy to the masses in a large number of day to day situations as well. Topical use of nano silver stem cell activators finds application in the treatment of burns, nonhealing wounds, ulcers, and impending gangrene thereby greatly reducing the risk of amputation of diabetic foot. Stem cell activation also helps to reduce post-surgical infections, surgical scars, and wound dehiscence to negligible levels which were previously unimaginable. Another topical application of great interest is epitomized in the case of "Fingertip Regrowth After Amputation". Nano silver stem cell activators can be dispersed into body fat, bone marrow, and cerebrospinal fluid to cause accelerated healing and regeneration. Applications of this technology are numerous and include, but are not limited to, facial and breast reconstructive surgeries or augmentation; spinal and brain injuries; bone marrow stem cell transplant; kidney, cardiac, pancreas repair and regenerations; nonhealing fractures and osteomyelitis. Case studies are presented in this paper with a series of before and after photos, progressively taken over a period of time, to demonstrate the vast and incredible capabilities of this stem cell activation therapy. Of great interest is the case study of "Fingertip Regrowth After Amputation" where the entire fingertip (including the fingernail and fingerprint) have been recreated in only 30 days, compared to the previous documented case using silver in 1995, which took a whole 90 days. Such an efficient and rapid regeneration is unprecedented. A fingernail in the human body normally grows at a steady pace which requires 5 to 6 months to replace its entire length. In this case however, the entire length is regenerated in only a 30 day period. This demonstrates the approximately five-fold accelerated healing and regeneration capabilities of nano silver stem cell activation as compared to unaided healing of the body. In vivo nano silver stem cell activation not only helps to dedifferentiate mature cells but also helps to provide a larger number of progenitor cells from existing stem cells, including those obtained through dedifferentiation, ensuring highly accelerated healing and regeneration. This will reduce the dependence on the harvesting of embryonic, cord blood, and adult stem cells. Thus, the benefits of stem cell regenerative medicine will enable the common man to pursue this line of treatment at a very reasonable and affordable cost.
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A method of producing local antibiotic effects by means of an iontophoretic technique using free silver ions has been evaluated in vitro and in vivo for more than two decades. The antibiotic properties of the technique have proved useful in both animal and human studies. In the course of determining the optimal clinical methodology for infected open wounds, a significant growth stimulation property resembling local tissue regeneration was noted. This has been traced to either the apparent production of dedifferentiation of normal mature cells or the stimulation of preexisting stem cells in the wound, resulting in the production of large numbers of progenitor cells. This process has now been studied in detail, and the results are presented herewith.